Back to all insights

Physical activity does wonders for your health

24 April 20265 min read

Being physically active is one of the most important things you can do for your health. This applies whether you are young or old, overweight or slim, untrained or an experienced athlete. The health benefits are immediate—and last a lifetime.

Good health encompasses both physical and mental well-being. It’s not just about avoiding illness or frailty, but also about feeling joy and enjoying a good quality of life in your daily routine (1).

At Mia Health, we help you stay physically active and achieve good health on your own terms.

What is physical activity?

Physical activity is any movement that increases your heart rate. Or, to use the official definition: “any bodily movement produced by skeletal muscles that results in a significant increase in energy expenditure above resting levels” (2).

When physical activity is planned, regular, and carried out with a specific goal, it is called exercise (2).

This goal could be, for example, to become healthier and slimmer. It could be to feel more energetic and make daily life easier. Or it could be to perform better in a specific activity or over a certain distance.

Physical activity and exercise can indeed contribute to all of this. And it doesn’t take much. In this article, we’ll walk you through the health benefits you can expect from being physically active—both immediately, in the slightly longer term, and for the rest of your life.

A woman walks her dog in a winter landscape
Physical activity is a miracle cure that benefits physical, mental, and social health. (Photo: Mia Health)

Immediate effects

You experience health benefits from physical activity immediately after your first workout. A single session boosts your mood, sharpens your mind, and helps your body better manage harmful sugars and fats circulating in your bloodstream.

Sharpen your mind and reduce fatigue

You may have heard that exercise “gives you energy.” It is well documented that you feel more energetic after a workout (3). And this feeling of having more energy contributes to less exhaustion and fatigue (1).

In fact, the brain functions better immediately after a workout. Among other things, reaction time decreases, you’re able to make decisions faster, and your ability to execute tasks improves (4, 5).

So after a tiring day, it’s not a long evening on the couch that brings back your energy and creativity. A short, effective workout, on the other hand!

Reduces anxiety

During and immediately after physical activity, the release of happiness and reward hormones such as dopamine, serotonin, and endorphins increases (6). This may explain why self-esteem increases after being physically active. You feel happy and content. You simply develop a more positive outlook on life (7, 8)!

Immediately after exercise, you’re also less prone to anxiety in stressful situations (9).

In other words: A little physical activity before a job interview, an important sales meeting, or a crucial exam can make it a less stressful experience.

winter happiness
Physical activity has immediate health benefits! Both during and right after you’ve been active, your body is flooded with neurotransmitters that make you feel more alert, energetic, happy, and mentally present.

Reduces appetite and improves sleep

If you struggle to fall asleep at night, a short half-hour of physical activity can help. People with sleep problems fall asleep more easily, sleep longer, and enjoy better sleep quality if they’ve been physically active before bedtime (10).

If you smoke, keep in mind that physical activity counteracts the urge to smoke both during and for quite some time after the activity (11).

And if your goal is to lose a few pounds, it’s good to know that you actually feel less hungry after working out. A single workout affects the release of hormones that regulate appetite (12). As a result, you typically don’t eat more in the hours after exercising than you otherwise would have, even though you’ve burned more calories (13).

Risk factors decrease

Your body is healthier after just one session of physical activity. Insulin sensitivity increases immediately (14), so that sugar is absorbed into the cells instead of circulating in the blood. For people with diabetes, this acute effect lasts for up to three days (15).

A combination of high blood sugar, unhealthy fats in the blood, and high levels of inflammation can damage blood vessel walls (16). Fortunately, levels of harmful fats also drop sharply after exercise (17, 18, 19). Additionally, there is strong evidence that exercise has an immediate anti-inflammatory effect (20).

And that’s not all: In the hours following a workout, blood pressure drops (21), and blood vessels become more elastic (22).

Significant effects after just a few weeks

It’s amazing to think that after just a single bout of physical activity, the body begins to make changes that lead to better health! But these effects last only a few hours, or at best a couple of days.

The key to achieving long-term adaptations is therefore to repeat the exercise regularly. It doesn’t take many weeks of physical activity, however, before the chronic health benefits start to show.

Better mental health and quality of life

One of these benefits is better mental health. Good mental or psychological health means feeling good about oneself and experiencing joy and well-being in life. If you have good mental health, you have, for example, few symptoms of anxiety and depression, and you feel less stressed at work and in daily life.

A good exercise program can undoubtedly provide significant benefits for mental health (23, 24).

Among other things, several studies show that regular exercise leads to reduced panic attacks and less social anxiety (25, 26). Additionally, exercise over time can reduce symptoms of depression (27) and lower stress levels (28, 29).

Regular physical activity makes you less prone to constant mood swings (30). Specifically, this means you’ll feel less angry, confused, exhausted, and tense than you did before you started exercising.

When you take all this into account, it’s perhaps not so surprising that physically active people generally have a better quality of life than those who are inactive (31, 32).

A sharper brain

There are likely many reasons why exercise improves mental health. Some of them are linked to lasting changes that occur in the brain when you exercise regularly (33).

Among other things, exercise leads to the formation of new brain cells (34, 35) and new blood vessels in the brain (36). The result is better memory (37). In addition, we become more attentive and better able to learn new things (38).

And as we’ll come back to: The risk of developing dementia decreases significantly for people who are regularly physically active.

father daughter skating on ice
Physical activity improves your quality of life, strengthens your brain, and gives you the energy to spend quality time with the people you love. (Photo: Mia Health)

Lower risk of disease

A few months of structured exercise is sufficient to lower most of the common risk factors for lifestyle-related diseases. Blood pressure drops (39), and blood cholesterol levels become healthier (40, 41).

Exercise is also effective at lowering blood sugar (42), especially for those who need it most (43).

Regular exercise also promotes healthier blood vessels. The diameter of the large arteries that carry blood from the heart increases, allowing blood to flow more easily through them. Additionally, the blood vessels’ ability to dilate increases (44). Exercise stimulates the growth of new small blood vessels around our muscles, which makes the muscles better able to absorb oxygen and nutrients carried by the blood (45).

Stronger Muscles and Skeleton

Overweight individuals can lose a few pounds after just a few months of exercise (46). But for health’s sake, it is perhaps even more important to know that exercise can remove fat from the body and replace it with muscle mass, both for overweight individuals and those of normal weight (47).

Exercise not only gives the body larger muscles, but the muscles also become stronger. Although strength training is naturally the most effective way to become stronger, endurance training can also increase muscle strength (48). And being physically strong is closely linked to good mental health and a reduced risk of disease (49, 50, 51, 52).

And just to be clear: It’s never too late to start exercising. Even after the age of 75, strength training leads to a significant increase in muscle mass and muscle strength (53).

Like muscles, the skeleton becomes stronger with exercise. In both younger and older adults, bone density increases in both the spine and thigh bones after a period of exercise (54, 55).

Better fitness and a stronger heart

There is a very close link between high endurance capacity and good health and quality of life (56, 57, 58, 59). Regular endurance training is the most effective method for improving endurance capacity (60, 61), but for untrained individuals, strength training also has some effect (62).

One of the main reasons why high endurance capacity leads to good health is that it requires a strong heart. Endurance training causes the heart to pump blood more efficiently to the rest of the body (45). The heart grows stronger, pumps more blood with each beat, and fills more effectively with blood between beats (63).

Exercise can even reverse some of the impairments and damage we see in diseased hearts, such as after a heart attack (63). In addition, exercise lowers your resting heart rate and makes the natural variation in your heart rhythm from beat to beat healthier (64, 65).

Makes everyday tasks easier

With a stronger heart, stronger muscles, and a lighter body, the tasks you perform every day become easier (66, 67). You use a smaller portion of your maximum capacity when carrying groceries home from the store, jumping on the trampoline with your 4-year-old, moving heavy furniture into your new apartment, and when running to catch the bus.

For older adults, the risk of falls and bone fractures decreases (66, 68).

It goes without saying that all of this is important for quality of life (31, 32, 59).

quality of life
Given all the physical and mental health benefits that physical activity provides, it’s no wonder that quality of life also improves.

Reduces the risk of many diseases

After a few months of regular physical activity, you may have reached your first activity goal. But fitness is a perishable commodity, and it doesn’t take many weeks of inactivity before you’ve fallen back to square one (69).

To achieve lasting changes in health and quality of life, you must repeat the activity over many years.

If you make physical activity a lifelong habit, you lay the foundation for a healthy old age and a long life.

Prevents cardiovascular disease and cancer

The list of diseases for which you can reduce your risk by being physically active is quite long. Physical inactivity is linked to an increased risk of at least 35 different chronic conditions (70).

This includes the vast majority of cardiovascular diseases, such as heart attack (71), high blood pressure (72), heart failure (73), stroke (74), and peripheral artery disease (75).

Obesity (76) and diabetes (77) can also be prevented by being physically active. The same applies to metabolic syndrome (78), which involves having both obesity and several other risk factors for cardiovascular disease.

Furthermore, at least ten types of cancer can be prevented by being physically active. These include colorectal cancer, breast cancer, lung cancer, uterine cancer, liver cancer, bladder cancer, and rectal cancer (79).

Prevents mental health disorders, dementia, and chronic pain

Physically active people are less likely to suffer from depression (80), anxiety (81), and cognitive impairments such as Alzheimer’s disease (82) and other types of dementia (83).

It is also worth noting that men and women who have been regularly physically active throughout their lives experience less physical pain (84). Physical activity prevents muscle loss as you age (85), and exercise also counteracts the development of osteoporosis (86), osteoarthritis (87), and rheumatoid arthritis (88).

Physical activity is medicine for the chronically ill

If you already have a chronic illness, there is no reason to stop exercising. Physical activity is effective medicine for at least 26 medical conditions (89).

Essentially, these are the same conditions that can be prevented through exercise. For example, exercise is effective in alleviating symptoms and improving the health of people with depression and anxiety, dementia, metabolic syndrome, cardiovascular diseases, COPD and other lung diseases, cancer, and various musculoskeletal disorders such as osteoporosis and arthritis (89).

As many have said before us: If physical activity were a pill, everyone would take it!

older
People who have been physically active throughout their lives have a lower risk of developing major health conditions as they get older. Being physically active not only helps you live longer, it also helps you live better.

Adding life to years

Given all this, it comes as no surprise that people who remain physically active throughout their lives live, on average, many years longer than those who are physically inactive (70). Now, perhaps not everyone has a goal in and of itself to live to such a ripe old age, but we must remember what this implies:

Exercise delays aging and reduces the risk of all the major public health diseases (70). This means that not only do you live longer if you are physically active, but you also spend the final years of your life in better health and with a higher quality of life (90).

Doesn’t reaching 100 in good health sound better than turning 80 and living with failing health for the last decade of your life?

Mia Health aims to be your hub and helping hand for physical activity and good health for the rest of your life.

With us, physical activity becomes not just a lifestyle, but a fun one at that! If you start today, you’ll feel the effects already… yes, today!

References

  1. World Health Organization. (2006). Constitution of the World Health Organization– Basic Documents, Forty-fifth edition, Supplement, October 2006. 
  2. Caspersen, C. J., Powell, K. E., & Christenson, G. M. (1985). Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public health reports, 100(2), 126. 
  3. Loy, B. D., O’Connor, P. J., & Dishman, R. K. (2013). The effect of a single bout of exercise on energy and fatigue states: a systematic review and meta-analysis. Fatigue: Biomedicine, Health & Behavior, 1(4), 223-242. 
  4. Ludyga, S., Gerber, M., Brand, S., Holsboer‐Trachsler, E., & Pühse, U. (2016). Acute effects of moderate aerobic exercise on specific aspects of executive function in different age and fitness groups: A meta‐analysis. Psychophysiology, 53(11), 1611-1626. 
  5. Kamijo, K., Hayashi, Y., Sakai, T., Yahiro, T., Tanaka, K., & Nishihira, Y. (2009). Acute effects of aerobic exercise on cognitive function in older adults. Journals of Gerontology: Series B, 64(3), 356-363. 
  6. Basso, J. C., & Suzuki, W. A. (2017). The effects of acute exercise on mood, cognition, neurophysiology, and neurochemical pathways: A review. Brain Plasticity, 2(2), 127-152. 
  7. Liao, Y., Shonkoff, E. T., & Dunton, G. F. (2015). The acute relationships between affect, physical feeling states, and physical activity in daily life: a review of current evidence. Frontiers in psychology, 6, 1975. 
  8. Reed, J., & Ones, D. S. (2006). The effect of acute aerobic exercise on positive activated affect: A meta-analysis. Psychology of Sport and Exercise, 7(5), 477-514. 
  9. Ensari, I., Greenlee, T. A., Motl, R. W., & Petruzzello, S. J. (2015). Meta‐analysis of acute exercise effects on state anxiety: An update of randomized controlled trials over the past 25 years. Depression and anxiety, 32(8), 624-634. 
  10. Passos, G. S., Poyares, D., Santana, M. G., Garbuio, S. A., Tufik, S., & Mello, M. T. (2010). Effect of acute physical exercise on patients with chronic primary insomnia. Journal of Clinical Sleep Medicine, 6(3), 270-275. 
  11. Roberts, V., Maddison, R., Simpson, C., Bullen, C., & Prapavessis, H. (2012). The acute effects of exercise on cigarette cravings, withdrawal symptoms, affect, and smoking behaviour: systematic review update and meta-analysis. Psychopharmacology, 222(1), 1-15. 
  12. Schubert, M. M., Sabapathy, S., Leveritt, M., & Desbrow, B. (2014). Acute exercise and hormones related to appetite regulation: a meta-analysis. Sports Medicine, 44(3), 387-403. 
  13. Schubert, M. M., Desbrow, B., Sabapathy, S., & Leveritt, M. (2013). Acute exercise and subsequent energy intake. A meta-analysis. Appetite, 63, 92-104. 
  14. Bird, S. R., & Hawley, J. A. (2017). Update on the effects of physical activity on insulin sensitivity in humans. BMJ open sport & exercise medicine, 2(1), e000143. 
  15. Asano, R. Y., Sales, M. M., Browne, R. A. V., Moraes, J. F. V. N., Júnior, H. J. C., Moraes, M. R., & Simões, H. G. (2014). Acute effects of physical exercise in type 2 diabetes: a review. World journal of diabetes, 5(5), 659. 
  16. Wang, J. C., & Bennett, M. (2012). Aging and atherosclerosis: mechanisms, functional consequences, and potential therapeutics for cellular senescence. Circulation research, 111(2), 245-259. 
  17. Søndergaard, E., Poulsen, M. K., Jensen, M. D., & Nielsen, S. (2014). Acute changes in lipoprotein subclasses during exercise. Metabolism, 63(1), 61-68. 
  18. Greene, N. P., Martin, S. E., & Crouse, S. F. (2012). Acute exercise and training alter blood lipid and lipoprotein profiles differently in overweight and obese men and women. Obesity, 20(8), 1618-1627. 
  19. Crouse, S. F., O’Brien, B. C., Rohack, J. J., Lowe, R. C., Green, J. S., Tolson, H. O. M. E. R., & Reed, J. L. (1995). Changes in serum lipids and apolipoproteins after exercise in men with high cholesterol: influence of intensity. Journal of Applied Physiology, 79(1), 279-286. 
  20. Metsios, G. S., Moe, R. H., & Kitas, G. D. (2020). Exercise and inflammation. Best Practice & Research Clinical Rheumatology, 34(2), 101504. 
  21. Carpio-Rivera, E., Moncada-Jiménez, J., Salazar-Rojas, W., & Solera-Herrera, A. (2016). Acute effects of exercise on blood pressure: a meta-analytic investigation. Arquivos brasileiros de cardiologia, 106, 422-433. 
  22. Dawson, E. A., Green, D. J., Timothy Cable, N., & Thijssen, D. H. (2013). Effects of acute exercise on flow-mediated dilatation in healthy humans. Journal of applied physiology, 115(11), 1589-1598. 
  23. Mikkelsen, K., Stojanovska, L., Polenakovic, M., Bosevski, M., & Apostolopoulos, V. (2017). Exercise and mental health. Maturitas, 106, 48-56. 
  24. Wegner, M., Helmich, I., Machado, S., E Nardi, A., Arias-Carrion, O., & Budde, H. (2014). Effects of exercise on anxiety and depression disorders: review of meta-analyses and neurobiological mechanisms. CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorders), 13(6), 1002-1014. 
  25. Jayakody, K., Gunadasa, S., & Hosker, C. (2014). Exercise for anxiety disorders: systematic review. British journal of sports medicine, 48(3), 187-196.
  26. Stonerock, G. L., Hoffman, B. M., Smith, P. J., & Blumenthal, J. A. (2015). Exercise as treatment for anxiety: systematic review and analysis. Annals of behavioral medicine, 49(4), 542-556. 
  27. Cooney, G. M., Dwan, K., Greig, C. A., Lawlor, D. A., Rimer, J., Waugh, F. R., … & Mead, G. E. (2013). Exercise for depression. Cochrane database of systematic reviews, (9).
  28. Gerber, M., & Pühse, U. (2009). Do exercise and fitness protect against stress-induced health complaints? A review of the literature. Scandinavian journal of public health, 37(8), 801-819. 
  29. Mücke, M., Ludyga, S., Colledge, F., & Gerber, M. (2018). Influence of regular physical activity and fitness on stress reactivity as measured with the trier social stress test protocol: A systematic review. Sports Medicine, 48(11), 2607-2622. 
  30. Lane, A. M., & Lovejoy, D. J. (2001). The effects of exercise on mood changes: The moderating effect of depressed mood. Journal of sports medicine and physical fitness, 41(4), 539-545. 
  31. Bize, R., Johnson, J. A., & Plotnikoff, R. C. (2007). Physical activity level and health-related quality of life in the general adult population: a systematic review. Preventive medicine, 45(6), 401-415. 
  32. Anokye, N. K., Trueman, P., Green, C., Pavey, T. G., & Taylor, R. S. (2012). Physical activity and health related quality of life. BMC public health, 12(1), 1-8. 
  33. Di Liegro, C. M., Schiera, G., Proia, P., & Di Liegro, I. (2019). Physical activity and brain health. Genes, 10(9), 720. 
  34. Van Praag, H. (2008). Neurogenesis and exercise: past and future directions. Neuromolecular medicine, 10(2), 128-140. 
  35. Ma, C. L., Ma, X. T., Wang, J. J., Liu, H., Chen, Y. F., & Yang, Y. (2017). Physical exercise induces hippocampal neurogenesis and prevents cognitive decline. Behavioural brain research, 317, 332-339. 
  36. Cotman, C. W., Berchtold, N. C., & Christie, L. A. (2007). Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends in neurosciences, 30(9), 464-472. 
  37. Pereira, A. C., Huddleston, D. E., Brickman, A. M., Sosunov, A. A., Hen, R., McKhann, G. M., … & Small, S. A. (2007). An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proceedings of the National Academy of Sciences, 104(13), 5638-5643. 
  38. Hillman, C. H., Erickson, K. I., & Kramer, A. F. (2008). Be smart, exercise your heart: exercise effects on brain and cognition. Nature reviews neuroscience, 9(1), 58-65. 
  39. Cornelissen, V. A., & Smart, N. A. (2013). Exercise training for blood pressure: a systematic review and meta-analysis. Journal of the American heart association, 2(1), e004473. 
  40. Fikenzer, K., Fikenzer, S., Laufs, U., & Werner, C. (2018). Effects of endurance training on serum lipids. Vascular pharmacology, 101, 9-20. 
  41. Wang, Y., & Xu, D. (2017). Effects of aerobic exercise on lipids and lipoproteins. Lipids in health and disease, 16(1), 1-8. 
  42. Boniol, M., Dragomir, M., Autier, P., & Boyle, P. (2017). Physical activity and change in fasting glucose and HbA1c: a quantitative meta-analysis of randomized trials. Acta diabetologica, 54(11), 983-991. 
  43. Umpierre, D., Ribeiro, P. A., Kramer, C. K., LeitŃo, C. B., Zucatti, A. T., Azevedo, M. J., … & Schaan, B. D. (2011). Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. Jama, 305(17), 1790-1799. 
  44. Ashor, A. W., Lara, J., Siervo, M., Celis-Morales, C., Oggioni, C., Jakovljevic, D. G., & Mathers, J. C. (2015). Exercise modalities and endothelial function: a systematic review and dose–response meta-analysis of randomized controlled trials. Sports medicine, 45(2), 279-296. 
  45. Hellsten, Y., & Nyberg, M. (2011). Cardiovascular adaptations to exercise training. Comprehensive Physiology, 6(1), 1-32. 
  46. Thorogood, A., Mottillo, S., Shimony, A., Filion, K. B., Joseph, L., Genest, J., … & Eisenberg, M. J. (2011). Isolated aerobic exercise and weight loss: a systematic review and meta-analysis of randomized controlled trials. The American journal of medicine, 124(8), 747-755. 
  47. Westerterp, K. R. (2018). Exercise, energy balance and body composition.European Journal of Clinical Nutrition, 72(9), 1246-1250. 
  48. Williams, M. A., Haskell, W. L., Ades, P. A., Amsterdam, E. A., Bittner, V., Franklin, B. A., … & Stewart, K. J. (2007). Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism. Circulation, 116(5), 572-584. 
  49. Volaklis, K. A., Halle, M., & Meisinger, C. (2015). Muscular strength as a strong predictor of mortality: a narrative review. European journal of internal medicine, 26(5), 303-310. 
  50. García-Hermoso, A., Cavero-Redondo, I., Ramírez-Vélez, R., Ruiz, J. R., Ortega, F. B., Lee, D. C., & Martínez-Vizcaíno, V. (2018). Muscular strength as a predictor of all-cause mortality in an apparently healthy population: a systematic review and meta-analysis of data from approximately 2 million men and women. Archives of physical medicine and rehabilitation, 99(10), 2100-2113. 
  51. Artero, E. G., Lee, D. C., Lavie, C. J., España-Romero, V., Sui, X., Church, T. S., & Blair, S. N. (2012). Effects of muscular strength on cardiovascular risk factors and prognosis.Journal of cardiopulmonary rehabilitation and prevention, 32(6), 351. 
  52. Marques, A., Gomez-Baya, D., Peralta, M., Frasquilho, D., Santos, T., Martins, J., … & Gaspar de Matos, M. (2020). The effect of muscular strength on depression symptoms in adults: a systematic review and meta-analysis. International journal of environmental research and public health, 17(16), 5674. 
  53. Grgic, J., Garofolini, A., Orazem, J., Sabol, F., Schoenfeld, B. J., & Pedisic, Z. (2020). Effects of resistance training on muscle size and strength in very elderly adults: a systematic review and meta-analysis of randomized controlled trials. Sports Medicine, 50(11), 1983-1999. 
  54. Kelley, G. A., Kelley, K. S., & Kohrt, W. M. (2013). Exercise and bone mineral density in premenopausal women: a meta-analysis of randomized controlled trials. International journal of endocrinology, 2013. 
  55. Marques, E. A., Mota, J., & Carvalho, J. (2012). Exercise effects on bone mineral density in older adults: a meta-analysis of randomized controlled trials. Age, 34(6), 1493-1515. 
  56. Imboden, M. T., Harber, M. P., Whaley, M. H., Finch, W. H., Bishop, D. L., & Kaminsky, L. A. (2018). Cardiorespiratory fitness and mortality in healthy men and women. Journal of the American College of Cardiology, 72(19), 2283-2292. 
  57. Kaminsky, L. A., Arena, R., Ellingsen, Ø., Harber, M. P., Myers, J., Ozemek, C., & Ross, R. (2019). Cardiorespiratory fitness and cardiovascular disease-the past, present, and future. Progress in cardiovascular diseases, 62(2), 86-93. 
  58. Kandola, A., Ashdown-Franks, G., Stubbs, B., Osborn, D. P. J., & Hayes, J. F. (2019). The association between cardiorespiratory fitness and the incidence of common mental health disorders: a systematic review and meta-analysis. Journal of affective disorders, 257, 748-757. 
  59. Sloan, R. A., Sawada, S. S., Martin, C. K., Church, T., & Blair, S. N. (2009). Associations between cardiorespiratory fitness and health-related quality of life. Health and Quality of Life Outcomes, 7(1), 1-5. 
  60. Scribbans, T. D., Vecsey, S., Hankinson, P. B., Foster, W. S., & Gurd, B. J. (2016). The effect of training intensity on VO2max in young healthy adults: a meta-regression and meta-analysis. International journal of exercise science, 9(2), 230. 
  61. Huang, G., Gibson, C. A., Tran, Z. V., & Osness, W. H. (2005). Controlled endurance exercise training and VO2max changes in older adults: a meta‐analysis. Preventive cardiology, 8(4), 217-225. 
  62. Ozaki, H., Loenneke, J. P., Thiebaud, R. S., & Abe, T. (2013). Resistance training induced increase in VO2max in young and older subjects. European Review of Aging and Physical Activity, 10(2), 107-116. 
  63. Moreira, J. B., Wohlwend, M., & Wisløff, U. (2020). Exercise and cardiac health: physiological and molecular insights. Nature Metabolism, 2(9), 829-839. 
  64. Sandercock, G. R., Bromley, P. D., & Brodie, D. A. (2005). Effects of exercise on heart rate variability: inferences from meta-analysis. Medicine and science in sports and exercise, 37(3), 433-439. 
  65. Winsley, R. (2002). Acute and chronic effects of exercise on heart rate variability in adults and children: A review. Pediatric Exercise Science, 14(4), 328-344. 
  66. Dipietro, L., Campbell, W. W., Buchner, D. M., Erickson, K. I., Powell, K. E., Bloodgood, B., … & Olson, R. D. (2019). Physical activity, injurious falls, and physical function in aging: an umbrella review. Medicine and science in sports and exercise, 51(6), 1303. 
  67. Liu, C. J., & Latham, N. K. (2009). Progressive resistance strength training for improving physical function in older adults. Cochrane database of systematic reviews, (3). 
  68. Marks, R. (2011). Physical activity and hip fracture disability: a review. Journal of aging research, 2011. 
  69. Mujika, I., & Padilla, S. (2001). Cardiorespiratory and metabolic characteristics of detraining in humans. Medicine and science in sports and exercise, 33(3), 413-421. 
  70. Booth, F. W., Roberts, C. K., & Laye, M. J. (2012). Lack of exercise is a major cause of chronic diseases. Comprehensive physiology, 2(2), 1143. 
  71. Winzer, E. B., Woitek, F., & Linke, A. (2018). Physical activity in the prevention and treatment of coronary artery disease. Journal of the American Heart Association, 7(4), e007725. 
  72. Huai, P., Xun, H., Reilly, K. H., Wang, Y., Ma, W., & Xi, B. (2013). Physical activity and risk of hypertension: a meta-analysis of prospective cohort studies. Hypertension, 62(6), 1021-1026. 
  73. Pandey, A., Garg, S., Khunger, M., Darden, D., Ayers, C., Kumbhani, D. J., … & Berry, J. D. (2015). Dose–response relationship between physical activity and risk of heart failure: a meta-analysis. Circulation, 132(19), 1786-1794. 
  74. Gallanagh, S., Quinn, T. J., Alexander, J., & Walters, M. R. (2011). Physical activity in the prevention and treatment of stroke. International Scholarly Research Notices, 2011. 
  75. Schiattarella, G. G., Perrino, C., Magliulo, F., Carbone, A., Bruno, A. G., De Paulis, M., … & Esposito, G. (2014). Physical activity in the prevention of peripheral artery disease in the elderly. Frontiers in physiology, 5, 12. 
  76. Lee, I. M., Djoussé, L., Sesso, H. D., Wang, L., & Buring, J. E. (2010). Physical activity and weight gain prevention.Jama, 303(12), 1173-1179. 
  77. Aune, D., Norat, T., Leitzmann, M., Tonstad, S., & Vatten, L. J. (2015). Physical activity and the risk of type 2 diabetes: a systematic review and dose–response meta-analysis. European journal of epidemiology, 30(7), 529-542. 
  78. Pattyn, N., Cornelissen, V. A., Eshghi, S. R. T., & Vanhees, L. (2013). The effect of exercise on the cardiovascular risk factors constituting the metabolic syndrome. Sports medicine, 43(2), 121-133. 
  79. Moore, S. C., Lee, I. M., Weiderpass, E., Campbell, P. T., Sampson, J. N., Kitahara, C. M., … & Patel, A. V. (2016). Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults. JAMA internal medicine, 176(6), 816-825. 
  80. Mammen, G., & Faulkner, G. (2013). Physical activity and the prevention of depression: a systematic review of prospective studies.American journal of preventive medicine, 45(5), 649-657. 
  81. Martinsen, E. W. (2008). Physical activity in the prevention and treatment of anxiety and depression. Nordic journal of psychiatry, 62(sup47), 25-29. 
  82. Meng, Q., Lin, M. S., & Tzeng, I. (2020). Relationship between exercise and Alzheimer’s disease: A narrative literature review. Frontiers in neuroscience, 14, 131. 
  83. Blondell, S. J., Hammersley-Mather, R., & Veerman, J. L. (2014). Does physical activity prevent cognitive decline and dementia?: A systematic review and meta-analysis of longitudinal studies. BMC public health, 14(1), 1-12. 
  84. Shiri, R., Coggon, D., & Falah-Hassani, K. (2018). Exercise for the prevention of low back pain: systematic review and meta-analysis of controlled trials. American journal of epidemiology, 187(5), 1093-1101. 
  85. Beckwée, D., Delaere, A., Aelbrecht, S., Baert, V., Beaudart, C., Bruyere, O., … & Bautmans, I. (2019). Exercise interventions for the prevention and treatment of sarcopenia. A systematic umbrella review. The journal of nutrition, health & aging, 23(6), 494-502. 
  86. Yuan, Y., Chen, X., Zhang, L., Wu, J., Guo, J., Zou, D., … & Zou, J. (2016). The roles of exercise in bone remodeling and in prevention and treatment of osteoporosis.Progress in Biophysics and Molecular Biology, 122(2), 122-130. 
  87. Valderrabano, V., & Steiger, C. (2010). Treatment and prevention of osteoarthritis through exercise and sports. Journal of aging research, 2011. 
  88. Di Giuseppe, D., Bottai, M., Askling, J., & Wolk, A. (2015). Physical activity and risk of rheumatoid arthritis in women: a population-based prospective study. Arthritis research & therapy, 17(1), 1-7. 
  89. Pedersen, B. K., & Saltin, B. (2015). Exercise as medicine–evidence for prescribing exercise as therapy in 26 different chronic diseases. Scandinavian journal of medicine & science in sports, 25, 1-72. 
  90. Ferrucci, L., Izmirlian, G., Leveille, S., Phillips, C. L., Corti, M. C., Brock, D. B., & Guralnik, J. M. (1999). Smoking, physical activity, and active life expectancy. American journal of epidemiology, 149(7), 645-653. 
Anders Revdal

Anders Revdal

24 April 2026